{"id":133,"date":"2026-06-02T15:10:26","date_gmt":"2026-06-02T13:10:26","guid":{"rendered":"https:\/\/perso.uclouvain.be\/corentin.claeys\/?page_id=133"},"modified":"2026-07-17T15:23:37","modified_gmt":"2026-07-17T13:23:37","slug":"publications","status":"publish","type":"page","link":"https:\/\/perso.uclouvain.be\/corentin.claeys\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\t\t
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2026 \u00a0 Cohesin\u2013axis interaction via a conserved Red1 motif promotes domain-specific DSB formation and Mek1 activation.<\/a> bioRxiv.<\/strong><\/em> Rajalingam A., Tsuruta Y., Roy T., Urdiain-Arraiza J, Alnaser H.F., Hiraga S., Claeys Bouuaert C., Murakami H.<\/p>

2026 \u00a0 Dimerization of the S. cerevisiae Spo11 core complex.<\/a> bioRxiv.<\/strong><\/em> A\u00eft Bella H., Survi M., Urdiain-Arraiza J., Daga D., Subramanian VV., Hochwagen A., Claeys Bouuaert C.<\/p>

2026\u00a0\u00a0 Insights into the recruitment of the H3K4me3 reader Spp1 by the meiotic double-strand break protein Mer2.<\/a> bioRvix.<\/strong><\/em> Liloku P., Alvarez-Melo D., Gisbert V.G., Mannaert S., Mechleb K., Derclaye S., Alsteens D., Volkov A.N., Sterckx Y.G.J., Claeys Bouuaert C.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2026\u00a0\u00a0 Recruitment of Mre11 to recombination sites during meiosis.<\/a> Nature Communications.<\/strong><\/em> Priyadarshini P., Survi M., El Yazidi Mouloud W., Bohn R., Ballet S., Hunter N., Volkov A.N., Claeys Bouuaert C.<\/p>

2025\u00a0\u00a0 In vitro reconstitution of SPO11-mediated DNA cleavage sheds new light on the initiation of meiotic recombination.<\/a> DNA Cell Biol.<\/strong><\/em> Oger C., Claeys Bouuaert C.<\/p>

2025\u00a0\u00a0 SPO11 dimers are sufficient to catalyse DNA double-strand breaks.<\/a> Nature.<\/strong><\/em> Oger C., Claeys Bouuaert C.<\/p>

2024\u00a0\u00a0 Cryo-EM structure of the Spo11 core complex bound to DNA.<\/a> Nature Structural & Molecular Biology.<\/strong><\/em> Yu Y., Wang J., Liu K., Zheng Z., Arter M., Claeys Bouuaert C., Pu S., Patel D.J., Keeney S.<\/p>

2023\u00a0\u00a0 Evolutionary conservation of the structure and function of meiotic Rec114-Mei4 and Mer2 complexes.<\/a> Genes & Development.<\/strong><\/em> Daccache D., De Jonge E., Liloku P., Mechleb K., Haddad M., Corthaut S., Sterckx Y.G., Volkov A.N., Claeys Bouuaert C.<\/p>

2021\u00a0\u00a0 DNA-driven condensation assembles the meiotic DNA break machinery.<\/a> Nature.<\/strong><\/em> Claeys Bouuaert, C., Pu S., Wang J., Oger C., Daccache D., Xie W., Patel D.J., Keeney S.<\/p>

2021\u00a0\u00a0 Mechanism and control of meiotic DNA double-strand break formation in S. cerevisiae.<\/a> Frontiers Cell Dev Biol.<\/strong><\/em> Yadav V.K., Claeys Bouuaert C.<\/p>

2021\u00a0\u00a0 Concerted cutting by Spo11 illuminates the mechanism of meiotic DNA break formation.<\/a> Nature.<\/strong><\/em> Johnson D., Crawford M., Cooper T., Claeys Bouuaert C., Keeney S., Llorente B., Garcia V., Neale M.J.<\/p>

2021\u00a0\u00a0 Structural and functional characterization of the Spo11 core complex.<\/a> Nature Structural & Molecular Biology.<\/strong><\/em> Claeys Bouuaert C., Tischfield S.E., Pu S., Mimitou E.P., Arias-Palomo E., Berger J.M., Keeney S.<\/p>

2017\u00a0\u00a0 Distinct DNA-binding surfaces in the ATPase and linker domains of MutLgamma determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair.<\/a> PLoS Genetics.<\/strong><\/em> Claeys Bouuaert, C., and Keeney, S<\/p>

2017\u00a0\u00a0 rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline.<\/a> PLoS Genetics.<\/strong><\/em> Jain, D., Meydan, C., Lange, J., Claeys Bouuaert, C., Mason, C.E., Anderson, K.V., and Keeney, S.<\/p>

2017\u00a0\u00a0 A single active site in the mariner transposase cleaves DNA strands of opposite polarity.<\/a> Nucleic Acids Research.<\/strong><\/em> Claeys Bouuaert, C., and Chalmers, R.<\/p>

2016\u00a0\u00a0 Breaking DNA.<\/a> Science.<\/strong><\/em> Claeys Bouuaert, C., and Keeney, S.<\/p>

2014\u00a0\u00a0 One to rule them all: A highly conserved motif in mariner transposase controls multiple steps of transposition.<\/a> Mobile Genetic Elements.<\/strong><\/em> Claeys Bouuaert, C., Tellier, M., and Chalmers, R.<\/p>

2014\u00a0\u00a0 Crosstalk between transposase subunits during cleavage of the mariner transposon.<\/a> Nucleic Acids Research.<\/strong><\/em> Claeys Bouuaert, C., Walker, N., Liu, D., and Chalmers, R.<\/p>

2013\u00a0\u00a0 The autoregulation of a eukaryotic DNA transposon.<\/a> Elife.<\/strong><\/em> Claeys Bouuaert, C., Lipkow, K., Andrews, S.S., Liu, D., and Chalmers, R.<\/p>

2013\u00a0\u00a0 Hsmar1 transposition is sensitive to the topology of the transposon donor and the target.<\/a> PLoS One.<\/strong><\/em> Claeys Bouuaert, C., and Chalmers, R.<\/p>

2011\u00a0\u00a0 A simple topological filter in a eukaryotic transposon as a mechanism to suppress genome instability.<\/a> Molecular and Cellular Biology.<\/strong><\/em> Claeys Bouuaert, C., Liu, D., and Chalmers, R.<\/p>

2010\u00a0\u00a0 Transposition of the human Hsmar1 transposon: rate-limiting steps and the importance of the flanking TA dinucleotide in second strand cleavage.<\/a> Nucleic Acids Research.<\/strong><\/em> Claeys Bouuaert, C., and Chalmers, R.<\/p>

2010\u00a0\u00a0 Gene therapy vectors: the prospects and potentials of the cut-and-paste transposons.<\/a> Genetica.<\/strong><\/em> Claeys Bouuaert, C., and Chalmers, R.M.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Preprints 2026 \u00a0 Cohesin\u2013axis interaction via a conserved Red1 motif promotes domain-specific DSB formation and Mek1 activation. bioRxiv. Rajalingam A., Tsuruta Y., Roy T., Urdiain-Arraiza J, Alnaser H.F., Hiraga S., Claeys Bouuaert C., Murakami H. 2026 \u00a0 Dimerization of the S. cerevisiae Spo11 core complex. bioRxiv. A\u00eft Bella H., Survi M., Urdiain-Arraiza J., Daga D., […]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ocean_front_end_style_editor":"no","ocean_post_layout":"full-screen","ocean_both_sidebars_style":"","ocean_both_sidebars_content_width":0,"ocean_both_sidebars_sidebars_width":0,"ocean_sidebar":"0","ocean_second_sidebar":"0","ocean_disable_margins":"enable","ocean_add_body_class":"","ocean_shortcode_before_top_bar":"","ocean_shortcode_after_top_bar":"","ocean_shortcode_before_header":"","ocean_shortcode_after_header":"","ocean_has_shortcode":"","ocean_shortcode_after_title":"","ocean_shortcode_before_footer_widgets":"","ocean_shortcode_after_footer_widgets":"","ocean_shortcode_before_footer_bottom":"","ocean_shortcode_after_footer_bottom":"","ocean_display_top_bar":"off","ocean_display_header":"default","ocean_header_style":"","ocean_center_header_left_menu":"0","ocean_custom_header_template":"0","ocean_custom_logo":0,"ocean_custom_retina_logo":0,"ocean_custom_logo_max_width":0,"ocean_custom_logo_tablet_max_width":0,"ocean_custom_logo_mobile_max_width":0,"ocean_custom_logo_max_height":0,"ocean_custom_logo_tablet_max_height":0,"ocean_custom_logo_mobile_max_height":0,"ocean_header_custom_menu":"0","ocean_menu_typo_font_family":"0","ocean_menu_typo_font_subset":"","ocean_menu_typo_font_size":0,"ocean_menu_typo_font_size_tablet":0,"ocean_menu_typo_font_size_mobile":0,"ocean_menu_typo_font_size_unit":"px","ocean_menu_typo_font_weight":"","ocean_menu_typo_font_weight_tablet":"","ocean_menu_typo_font_weight_mobile":"","ocean_menu_typo_transform":"","ocean_menu_typo_transform_tablet":"","ocean_menu_typo_transform_mobile":"","ocean_menu_typo_line_height":0,"ocean_menu_typo_line_height_tablet":0,"ocean_menu_typo_line_height_mobile":0,"ocean_menu_typo_line_height_unit":"","ocean_menu_typo_spacing":0,"ocean_menu_typo_spacing_tablet":0,"ocean_menu_typo_spacing_mobile":0,"ocean_menu_typo_spacing_unit":"","ocean_menu_link_color":"","ocean_menu_link_color_hover":"","ocean_menu_link_color_active":"","ocean_menu_link_background":"","ocean_menu_link_hover_background":"","ocean_menu_link_active_background":"","ocean_menu_social_links_bg":"","ocean_menu_social_hover_links_bg":"","ocean_menu_social_links_color":"","ocean_menu_social_hover_links_color":"","ocean_disable_title":"on","ocean_disable_heading":"default","ocean_post_title":"","ocean_post_subheading":"","ocean_post_title_style":"","ocean_post_title_background_color":"","ocean_post_title_background":0,"ocean_post_title_bg_image_position":"","ocean_post_title_bg_image_attachment":"","ocean_post_title_bg_image_repeat":"","ocean_post_title_bg_image_size":"","ocean_post_title_height":0,"ocean_post_title_bg_overlay":0.5,"ocean_post_title_bg_overlay_color":"","ocean_disable_breadcrumbs":"default","ocean_breadcrumbs_color":"","ocean_breadcrumbs_separator_color":"","ocean_breadcrumbs_links_color":"","ocean_breadcrumbs_links_hover_color":"","ocean_display_footer_widgets":"off","ocean_display_footer_bottom":"off","ocean_custom_footer_template":"0","footnotes":""},"class_list":["post-133","page","type-page","status-publish","hentry","entry"],"_links":{"self":[{"href":"https:\/\/perso.uclouvain.be\/corentin.claeys\/wp-json\/wp\/v2\/pages\/133","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/perso.uclouvain.be\/corentin.claeys\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/perso.uclouvain.be\/corentin.claeys\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/perso.uclouvain.be\/corentin.claeys\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/perso.uclouvain.be\/corentin.claeys\/wp-json\/wp\/v2\/comments?post=133"}],"version-history":[{"count":22,"href":"https:\/\/perso.uclouvain.be\/corentin.claeys\/wp-json\/wp\/v2\/pages\/133\/revisions"}],"predecessor-version":[{"id":9014,"href":"https:\/\/perso.uclouvain.be\/corentin.claeys\/wp-json\/wp\/v2\/pages\/133\/revisions\/9014"}],"wp:attachment":[{"href":"https:\/\/perso.uclouvain.be\/corentin.claeys\/wp-json\/wp\/v2\/media?parent=133"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}