Recent news
On November 28, David Alsteens receives the BAEF Alumni Award 2019 in the field of Biomedical Sciences.
Congrats to Melanie, Andra and Jinsung for the brillant study published in Nature Communications about reovirus binding to cell surfaces. Combination of AFM with confocal microscopy revealed how sialic acid binding to σ1 trigger a conformational change during virus early binding to cells.
Welcome to Dr. Danahe Mohammed and Rita Natividade. Danahe comes from Harvard University (David Weitz's lab) and will work on reovirus binding to cell. Rita did her master in University of Minho in Braga (Portugal) and starts a PhD in the lab.
David Alsteens Receives 2019 Heinrich Emanuel Merck Award for Analytical Science for "his groundbreaking investigations revealing the molecular mechanisms established by viruses to hijack the cellular barrier and enter the cell".
Congrats to Andra Dumitru and Simon Petitjean to be awarded with the prestigious positions of 'postdoctoral researcher' and 'research follow' of the FNRS, respectively.
The nBIO lab is now part of the WELBIO, an inter-university life sciences research institute funded by the Walloon Region.
In a few weeks, we will host the ISPM 2019 in Louvain-La-Neuve at the Martin's hotel. The programe is now online. Opening Lecture by Prof. Hermann Gaub! Looking forward to seeing you there!
Congrats to Martin for the new paper in ACS Chem. Biol. In collaboration with Marta Bally (Umea University, Sweden), we charactized HSV-1 binding to cellular GAGS and deciphered the role of the mucin-like region using AFM and SPT.
Review in the first issue of Nature Reviews Physics. How AFM can address question in mechanobiology?
In coll. with D. Tyteca (de Duve Institute, UCL), we specifically localized lipid using derivatized AFM probes with toxins. Congrats to Andra & Cristina!
Cristina is awarded with a long-term EMBO post-doc fellowship!!! AMAZING! Let's celebrate it soon!
Congrats. Martin won the belgian MT180 (My thesis in 180 second). He will represent french speaking part of Belgium at the international level in Switzerland in September! Good luck & May the force be with you ;-)!
Candidates with strong backroung in biophysics and/or cell biology are encourage to apply. Starting date asap ;-)
In collaboration with Knoops' team at LIBST, we used AFM to demonstrate how PRDX5 acts as Damage Associate molecular pattern and activate TLR4. Enjoy reading this story of how AFM can help in Immunology.
Just on time ;-)! New paper in Nanoscale Horizons on the study of membrane architecture of red bloods cells. How lipids organize in nanodomains in both physiological and pathological conditions.
Welcome to Dr. Jinsung Yang from South Korea. He will work on the NanoVirus ERC project. As a cell biologist, he will open a new world within the lab!
The lab is granted with a prestigious grant from the European Research Council (ERC), an ERC Starting Grant. The project entitled «Deciphering virus-host interactions using correlated confocal-atomic force microscopy» (NanoVirus) is scheduled to start in January 2018.
Welcome to Dr. Cristina Lo Giudice from the Centre of bionano interactions, University College Dublin. Cristina will study interaction between nanoparticles and cellular surfaces.
David presented us his cantilever-based instrument able to measure fast fluctuation mass of single adherent cells. In the evening, he tried to measure mass "mayonnaise" sauce on Belgian frittes :-)
Congrats to Melanie for the prestigious Schrödinger Fellowship. Cheers ;-) .
Together with Andra, we hosted the Bruker Webinar : "High-Resolution Imaging and Nanomechanical Mapping of Virus Binding Sites to Animal Cells".
Welcome to Dr. Melanie Köhler. Melanie did her thesis in Peter Hinterdorfer's lab in Linz (Austria) where she gained experience in single-molecule recognition by AFM.
In this research article, we used FD curve-based AFM to map single-virus binding to living mamalian cells. We extracted the knetics and thermodynamics of the bonds established at the first touch-down!
Welcome to Dr Andra-Cristina Dumitru, from the Ricardo Garcia's lab in Madrid. She will investigate the nanmechanics of Red blood cells.
David receives the Outstanding paper award 2015 of the European Microscopy Society (EMS) for his recent paper in Nature Methods.
Congrats to Andra-Cristina Dumitru for being awarded a prestigious Move In Louvain Postdoc fellowship for 2 years
In this research paper, we bifunctionalize AFM tips with two different ligands to probe the localization and orientation of single human cell membrane receptor in lipid membrane.
Welcome to Martin Delguste my first PhD student. As a high-level athlete running he started in October a race of 4 years ;-) during which he will study the cell - herpersvirus interactions. Good luck
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