NanoBiophysics lab - Prof. David Alsteens

"Single-molecule investigation of the binding interface stability of SARS-CoV-2 variants with ACE2"

A. Ray, T. T. Min Tran, R. d. S. Natividade, R.A. Moreira, J.D. Simpson, D. Mohammed, M. Koehler, S. J.L Petitjean, Q. Zhang, F. Bureau, L. Gillet, A.B. Poma,D. Alsteens
ACS Nanosciene Au (2024),4 (2) 136-145 →Link

"Piezo1 regulation involves lipid domains and the cytoskeleton and is favored by the atomatocyte–discocyte–echinocyte transformation"

A. Stommen, M. Ghodsi, A.-S. Cloos, L. Conraard, A.C. Dumitru, P. Henriet, C.E. Pierreux, D. Alsteens, D. Tyteca
biomolecules (2024),14(1) 51 →Link

"Plasma membrane nanodeformations promote actin polymerization through CIP4/CDC42 recruitment and regulate type II IFN signaling"

B. Ledoux, N. Zanin, J. Yang, V. Mercier, C. Coster, C. Dupont-Gillain, D. Alsteens, P. Morsomme, H.-F. Renard
Sci. Adv. (2023),9 (50) eade1660 →Link

"In-depth analysis of the pancreatic extracellular matrix during development for next-generation tissue engineering"

L. Glorieux, L. Vandooren, S. Derclaye, S. Pyr di Ruys, P. Oncina-Gil, A. Salowka, G. Herinckx, E. Aajja, P. Lemoine, C. Spourquet, H. Lefort, P. Henriet, D. Tyteca, F.M. Spagnoli, D. Alsteens, D. Vertommen, C.E. Pierreux
Int. J. Mol. Sci. (2023),24 (12) 10628 →Link

"Heparin-induced allosteric changes in SARS-CoV-2 spike protein facilitate ACE2 binding and viral entry"

S.J.L. Petitjean, S. Eeckhout, M. Delguste, Q. Zhang, K. Durlet, D. Alsteens
Nano Lett. (2023),23 (24) 11678 - 11684 →Link

"Deciphering molecular mechanisms stabilizing the reovirus-binding complex"

R. dos Santos Natividade, M. Koehler, P.S.F.C. Gomes, J.D. Simpson, S.C. Smith, D.E.B. Gomes, J. de Lhoneux, J. Yang, A. Ray, T.S. Dermody, R. C. Bernardi, K.M. Ogden, D. Alsteens
Proc. Natl. Acad. Sci. U.S.A. (2023),120 (21) e222074112 →Link

"Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus"

P. Shang, J.D. Simpson,G.M. Taylor, D.M. Sutherland, O.L. Welsh, P. Aravamudhan, R. dos Santos Natividade, K. Schwab, J.J. Michel, A.C. Poholek, Y. Wu, D. Rajasundaram, M. Koehler, D. Alsteens, T. Dermody
Nature Commun. (2023),14, 2615 →Link

"AFM-based force spectroscopy unravels stepwise formation of the DNA transposition complex in the widespread Tn3 family mobile genetic elements"

M. Fernadez, A.V. Shkumatov, Y. Liu, C. Stulemeijer, S. Derclaye, R.G. Efremov, B. Hallet, D. Alsteens
Nucleic Acid Research (2023), 51 (10) 4929-4941 →Link

"Single-molecule analysis of SARS-CoV-2 binding to C-type lectin receptors"

J.D. Simpson, A. Ray, C. Marcon, R. dos Santos Natividade, G. Mohammad Dorrazehi, K. Durlet, M. Koehler, D. Alsteens
Nano Lett. (2023),23 (4) 1496-1504 →Link

"Cholesterol and sphingomyelin polarize at the leading edge of migrating myoblasts and involve their clustering in submicrometric domains"

J. Vanderroost, N. Avalosse, D. Mohammed, D. Hoffmann, P. Henriet, C.E. Pierreux, D. Alsteens, D. Tyteca
biomolecules (2023),13(2), 3194 →Link

"Multivalent 9-O-Acetylated-sialic acid glycoclusters as potent inhibitors for SARS-CoV-2 infection"

S. J. L. Petitjean, W. Chen, M. Koehler, R. Jimmidi, J. Yang, D. Mohammed, B. Juniku, M. Stanifer, S. Boulant, S. Vincent, D. Alsteens
Nature Commun. (2022),13, 2564 →Link + Video Abstract →Link

"Surface cholesterol-enriched domains specifically promote invasion of breast cancer cell lines by controlling invadopodia and extracellular matrix degradation"

M. Maja, D. Mohammed, A.C. Dumitru, S. Verstraeten, M. Lingurski, M.-P. Mingeot-Leclercq, D. Alsteens, D. Tyteca
Cellular and Molecular Life Sciences (2022), 79, 417 →Link

"Salvia miltiorrhiza Bunge as a Potential Natural Compound against COVID‐19"

S.J.L. Petitjean, M. Lecocq, C. Lelong, R. Denis, S. Defrère, P.-A. Mariage, D. Alsteens, C. Pilette
Cells (2022), 11, 1311 →Link

"Atomic force microscopy applied to interrogate nanoscale cellular chemistry and supramolecular bond dynamics for biomedical applications"

J. D. Simpson, A. Ray, M. Koehler, D. Mohammed & D. Alsteens
Chemical Communications (2022) →Link

"Stepwise enzymatic-dependent mechanism of Ebola virus binding to cell surface receptors monitored by AFM"

Q. Zhang, J. Yang, S. Tilleux, Z. Guo, R.d.S. Natividade, M. Koehler, S. Petitjean, Z. Cui & D. Alsteens
Nano Letters (2022) 22, 1641-1648 →Link

"Nanophysical mapping of inflammasome activation by nanoparticles via specific cell surface recognition events"

C. Lo Giudice, J. Yang, M.A. Poncin, L. Adumeau, M. Delguste, M. Koehler, K. Evers, A.C. Dumitru, K.A. Dawson & D. Alsteens
ACS Nano (2022) 16, 306-316 →Link

"Molecular insights into receptor binding energetics and neutralization of SARS-CoV-2 variants"

M. Koehler, A. Ray, R.A. Moreira, B. Juniku, A.B. Poma & D. Alsteens
Nature Communications (2021) 12, 6977 →Link

"Role of the redox state of Human Peroxiredoxin-5 on its TLR4-activating DAMP function"

M.A. Poncin, P. Van Meerbeeck, J.D. Simpson, A. Clippe, F. Tyckaert, F. Bouillienne, H. Degand, A. Matagne, P. Morsomme, B. Knoops & D. Alsteens
antioxydants (2021) 10, 1902 →Link

"Altered Glycan Expression on Breast Cancer Cells Facilitates Infection by T3 Seroptype Oncolytic Reovirus"

D. Mohammed, M. Koehler, A.C. Dumitru, P. Aravamudhan, D.M. Sutherland, T.S. Dermody & David Alsteens
Nano Letters (2021) 21, 9720–9728 →Link

"Force spectroscopy of single cells using atomic force microscopy"

A. Viljoen, M. Mathelié-Guinlet, A. Ray, N. Strohmeyer, Y. Jin Oh, P. Hinterdorfer, D.J. Müller, D.Alsteens & Y.F. Dufrêne
Nature Rev. Meth. Primers (2021) 1, 63 →Link

"Probing PIEZO1 Localization upon Activation Using High-Resolution Atomic Force and Confocal Microscopy"

A.C. Dumitru, A. Stommen, M. Koehler, A.S. Cloos, J. Yang, A. Leclercqz, D. Tyteca and D. Alsteens
Nano Letters (2021) 12, 4950-4958 →Link

"Rotavirus Binding to Cell Surface Receptors Directly Recruiting α2 Integrin"

J. Yang, J. Park, M. Koehler, J. Simpson, Da. Luque, J. M. Rodríguez, D. Alsteens
Adv. Nanobiomed Res. in Press →Link

"Reovirus directly engages integrin to recruit clathrin for entry into host cells"

M. Koehler, S.J.L. Petitjean, J. Yang, P. Aravamudhan, X. Somoulay, C. Lo Giudice, M.A. Poncin, A.C. Dumitru, T.S. Dermody, D. Alsteens
Nature Communications (2021) 12, 2149 →Link + Video Abstract →Link

"Liquid–Liquid Phase Separation Enhances TDP-43 LCD Aggregation but Delays Seeded Aggregation"

D. Pakravan, E. Michiels,..., D. ALsteens, S. Derclaye,..., L. Van Den Bosh
Biomolecules (2021) 11(4), 548 →Link

"Impaired Cytoskeletal and Membrane Biophysical Properties of Acanthocytes in Hypobetalipoproteinemia – A Case Study"

A.S. Cloos, L.G. Daenen, ..., A.C. Dumitru, ...,D. Alsteens, R. van Wijk, D. Tyteca
Frontiers in Physiology (2021) 12:638027 →Link

"Atomic Force Microscopy-Based Force Spectroscopy and Multiparametric Imaging of Biomolecular and Cellular Systems"

D.J. Mueller, A.C. Dumitru, C. Lo Giudice, H.E. Gaub, P. Hinterdorfer, G. Hummer, J.J. De Yoreo, Y.F. Dufrêne, D. Alsteens
Chemical Reviews (2021) In press →Link

"Stress-Induced Catch-Bonds to Enhance Bacterial Adhesion"

M. Mathelié-Guinlet, F. Viela, D. Alsteens, Y.F. Dufrêne
Trends in Microbiology (2021) In press →Link

"Single-Virus Force Spectroscopy Discriminates the Intrinsic Role of Two Viral Glycoproteins upon Cell Surface Attachment"

M. Delguste, G. Le Brun, F. Cotin, B. Machiels, L. Giller, D.Alsteens
Nano Letters (2021) 21, 847-853 →Link

"Submolecular probing of the complement C5a receptor–ligand binding reveals a cooperative two-site binding mechanism"

A.C. Dumitru, R.N.V. K. Deepak, H. Liu, M. Koehler, C. Zhang, H. Fan, D. Alsteens
Communications Biology (2020) 3, 786 →Link

"Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor"

J. Yang, S. J.L. Petitjean, M. Koehler, Q. Zhang, A C. Dumitru, W. Chen, S. Derclaye, S.P. Vincent, P. Soumillion, D. Alsteens
Nat. Commun. (2020) 11, 4541 →Link

"Label‐Free Imaging of Cholesterol Assemblies Reveals Hidden Nanomechanics of Breast Cancer Cells"

A.C. Dumitru, D. Mohammed, M. Maja, J. Yang, S. Verstraeten, A. del Campo, M.-P. Mingeot-Leclercq, D. Tyteca, D. Alsteens
Advanced Science (2020) 22, 2002643 →Link

"Force-clamp spectroscopy identifies a catch bond mechanism in a Gram-positive pathogen"

M. Mathelié-Guinlet, F. Viela, G. Pietrocola, P. Speziale, D. Alsteens, Y. F. Dufrêne
Nat. Commun. (2020) 11, 5431 →Link

"Reovirus σ1 conformational flexibility modulates the efficiency of host cell attachment"

J.R. Diller, S.R. Halloran, M. Koehler, R. Dos Santos Natividade, D. Alsteens, T. Stehle, T.S. Dermody, K.M. Ogden
J. Virol. (2020) 23 →Link

"Multiparametric Atomic Force Microscopy Identifies Multiple Structural and Physical Heterogeneities on the Surface of Trypanosoma brucei"

C. Valotteau, A.C. Dumitru, L. Lecordier, D. Alsteens, E. Pays, D. Pérez-Morga, Y.F. Dufrêne
ACS Omega (2020) 5, 20953-20959 →Link

"The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity"

L. Lecordier, S. Uzureau, ..., A.C. Dumitru,..., D. Alsteens, ..., E. Pays
iScience (2020) 23, 101476 →Link

"Mechanochemical Activation of Class-B G-Protein-Coupled Receptor upon Peptide–Ligand Binding"

C. Lo Giudice, H. Zhang, B. Wu, D. Alsteens
Nano Lett. (2020) 20, 5575-5582 →Link

"Initial step of virus entry: Virion binding to cell-surface glycans"

M. Koehler, M. Delguste, C. Sieben, L. Gillet , D. Alsteens
Ann. Rev. Virol. (2020) 7, In press →Link

"Control of ligand-binding specificity using photocleavable linkers in AFM force spectroscopy"

M. Koehler, C. Lo Giudice, P. Vogl. A. Ebner, P. Hinterdorfer, H.J. Gruber, D. Alsteens
Nano Lett. (2020) 20, 4038-4042 →Link

"Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166."

H-F. Renard, F. Tyckaert, Cristina Lo Giudice, T. Hirsch, C.A. Valades-Cruz, C. Lemaigre, M. Shafaq-Zadah, C. Wunder, R. Wattiez, L. Johannes, P. van der Bruggen, D. Alsteeens, P. Morsomme
Nat. Commun. (2020) 11 →Link

"Glycan-mediated enhancement of reovirus receptor binding"

M. Koehler, P. Aravamudhan, C. Guzman-Cardozo, A.C. Dumitru, J. Yang, S. Gargiulo, P. Soumillion, T.S. Dermody, D. Alsteens
Nat. Commun. (2019) 10, 4460 →Link

"Probing ligand-receptor bonds in physiologically relevant conditions using AFM"

C. Lo Giudice, A.C. Dumitru, D. Alsteens
Anal. Bioanal. Chem. (2019) 25, 6549-6559 →Link

"Regulatory mechanisms of the mucin-like region on Herpes Simplex virus during cellular attachment"

M. Delguste, N. Peerboom, G. Le Brun, E. Trybala, S. Olofsson, T. Bergström, D. Alsteens, M. Bally
ACS Chem. Biol. (2019) 14, 534-542 →Link

"Seeing and sensing single G protein-coupled receptors by atomic force microscopy"

K.T. Sapra, P.M. Spoerri, A. Engel, D.Alsteens, D.J. Müller
Curr. Opin. Cell. Biol. (2019) 57, 25-32 →Link

"Atomic force microscopy-based mechanobiology"

M. Krieg, G. Fläschner, D.Alsteens, B.M. Gaub, W.H. Roos, G.J.L. Wuite, H.E. Gaub, C. Gerber, Y.F. Dufrêne, D.J. Müller
Nat. Rev. Phys (2019) 1 →Link

"Multivalent binding of herpesvirus to living cells is tightly regulated during infection"

M. Delguste, C. Zeippen, B. Machiels, J. Mast, L. Gillet, D.Alsteens
Science Advances (2018) 4, eaat1273 →Link

"A molecular mechanism for Wnt ligand-specific signaling"

M. Eubelen, N.Bostaille, P. Cabochette, A. Gauquier, P. Tebabi, A.C. Dumitru, M. Koehler, P. Gut, D.Alsteens, D.Y. Stainier, A. Garcia-Pino, B. Vanhollebeke
Science (2018) eaat1178 →Link

"High-resolution mapping and recognition of lipid domains using AFM with toxin-derivatized probes"

A.C. Dumitru, M.A., L. Conrad, C. Lo Giudice, P. Henriet, M. Veiga-da-Cunha, S. Derclaye, D. Tyteca, D. Alsteens
Chem. Commun. (2018) 54, 6903-6906 →Link

"Specific Interactions Measured by AFM on Living Cells between Peroxiredoxin-5 and TLR4: Relevance for Mechanisms of Innate Immunity"

B. Knoops, S. Becker, M.A. Poncin, J. Glibert, S. Derclaye, A. Clippe, D. Alsteens
Cell Chem. Biol. (2018) 25, 550-559 →Link

"Mechanical Forces Guiding Staphylococcus aureus Cellular Invasion"

V. Prystopiuk, C. Feuillie, P. Herman-Bausier, F. Viela, D. Alsteens, G. Pietrocola, P. Speziale, Y.F. Dufrêne
ACS Nano (2018) 12, 3609-3622 →Link

"Topography imaging of herpesvirus in native condition using atomic force microscopy"

M. Delguste, M. Koehler, L. Gillet, D. Alsteens
Clin. Microbiol. Infect. (2018) 24, 610-611 →Link

"Nanoscale membrane architecture of healthy and pathological red blood cells"

A.C. Dumitru, M.A. Poncin, L. Conrad, Y.F. Dufrêne, D. Tyteca, D. Alsteens
Nanoscale Horiz. (2018) 3, 293-304 →Link

"Combining confocal and atomic force microscopy to quantify single-virus binding to mammalian cell surfaces"

R. Newton, M. Delguste, M. Koehler, A.C. Dumitru, P.R. Laskowski, D.J. Müller, D. Alsteens
Nat. Protoc. (2017) 11, 2275-2292 →Link

"Biophysics: Rapid mass changes measured in cells"

D. Alsteens & Y.F. Dufrêne
Nature (2017) 550, 465-466 →Link

"Force-induced strengthening of the interaction between Staphylococcus aureus clumping factor B and loricrin"

P. Vitry, C. Valotteau, C. Feuillie, S. Bernard, D. Alsteens, J.A. Geoghegan, Y.F. Dufrêne
mBio (2017) 6, e01748-17 →Link

"Atomic force microscopy-based characterization and design of biointerfaces"

D. Alsteens, H. E. Gaub, R. Newton, M. Pfreundschuh, C. Gerber, D. J. Müller
Nat. Rev. Mat. (2017) 2, e17008 →Link

"Imaging modes of atomic force microscopy for application in molecular and cell biology."

Y.F. Dufrêne, T. Ando, R. Garcia, D. Alsteens, D. Martinez-Martin, A. Engel, C. Gerber, D.J. Müller
Nat. Nanotechnol. (2017) 12, 295-307 →Link

"Multiparametric atomic force microscopy imaging of biomolecular and cellular systems"

D. Alsteens, D.J.M. Müller, Y.F. Dufrêne
Acc. Chem. Res. (2017) 50, 924-931 →Link

"Nanomechanical mapping of first binding steps of a virus to animal cells"

D. Alsteens*, R. Newton, R. Schubert, D. Martinez-Martin, M. Delguste, B. Roska, D.J. Müller
Nat. Nanotechnol. (2017) 12, 177-183. (*Corresponding authors) →Link

"The biomechanical properties of an epithelial tissue determine the location of its vasculature"

M. Kragl, R. Schubert, C. Chen, D. Eberhard, D. Alsteens, M. Heni, H.-U. Häring, S. Speier, D.J. Müller & E. Lammert
Nat. Commun. (2016) 7, e13560.→Link

"Mechanical strength and inhibition of the Staphylococcus aureus collagen-binding protein Cna"

P. Herman-Bausier, C. Valotteau, G. Pietrocolab, S. Rindib, D. Alsteensa, T.J. Fosterc, P. Spezialeb, Y.F. Dufrêne
mBio (2016) 7, e01529-16 →Link

"Study of membrane receptors by atomic force microscopy"

D. Alsteens
Med./Sci. (2016) 5, 433-435

"Imaging single G-protein coupled receptors while quantifying their binding to two different ligands"

M. Pfreundschuh*, D. Alsteens*, R. Wieneke, C. Zhang, S. Coughlin, R. Tampé, B. Kobilka, D.J. Müller
Nat. Commun. (2015) 6, e8857. (*Contributed equally to this work) →Link

"Imaging of G-protein coupled receptors while quantifying their ligand-binding free energy landscape"

D. Alsteens*, M. Pfreundschuh, C. Zhang, P. Spoerri, S. Coughlin, B. Kobilka, D.J. Müller
Nat. Methods. (2015) 12, 845-851. (*Corresponding author) →Link

"Single-molecule force spectroscopy of membrane proteins from membranes freely spanning across nanoscopic pores"

R. Petrosyan, C. Bippes, S.Walheim, D. Harder, D. Fotiadis, T. Schimmel, D. Alsteens, D.J. Müller
Nano Letters (2015) 15, 3624-3633 →Link

"Force nanoscopy of hydrophobic interactions in the fungal pathogen Candida glabrata"

S. El-Kirat-Chatel, A. Beaussart, S. Derclaye, D.Alsteens, S. Kucharikova, P. Van Dijck, Y. Dufrêne
ACS Nano (2015) 9, 1648-1655

"Towards high-throughput biomechanical phenotyping of single molecules"

D. Alsteens, S. Tay, D.J. Müller
Nat. Methods (2015) 12, 45-46→Link

"Localizing chemical groups while imaging single native proteins by high-resolution AFM"

M. Pfreundschuh*, D. Alsteens*, M. Hilbert, M.O. Steinmetz, D.J. Müller

Nano Letters (2014) 14, 2957-2964.(*Contributed equally to this work)

Link

"Atomic force and electron microscopic-based study of sarcolemmal surface of living cardiomyocytes unveils unexpected mitochondrial shift in heart failure"

E. Dague, G. Genet, V. Lachaize, C. Guilbeau-Frugier, J. Fauconnier, C. Mias, B. Payre, L. Chopinet, D. Alsteens, S. Kasas, C. Severac, J. Thireau, C. Heymes, B. Honton, A. Lacampagne, A. Pathak, J.M. Senard, C. Gales

Journal of Molecular and Cellular Cardiology (2014) 74, 162-172.

Link

"Quantifying the forces guiding microbial cell adhesion using single-cell force spectroscopy"

A. Beaussart, S. El-Kirat-Chatel, R.M.A Sullan, D. Alsteens, P. Herman, S. Derclaye, Y.F. Dufrêne

Nat. Protocols (2014) 9, 1049-1055.

Link

"Multiparametric atomic force microscopy imaging of single bacteriophage extruding from living bacteria"

D. Alsteens, H. Trabelsi, P. Soumillion, Y.F. Dufrêne

Nat. Commun. (2013) 4, e2926.

"Quantifying the forces driving cell-cell adhesion in a fungal pathogen"

D. Alsteens, P. Van Dijck, P.N. Lipke, Y.F. Dufrêne

Langmuir (2013) 29, 13473-13480.

"Atomic force microscopy: a new look at pathogens"

D. Alsteens, A. Beaussart, S. El-Kirat-Chatel, R.M.A. Sullan, Y.F. Dufrêne

PLoS Pathogens (2013) 9, e1003516.

"Multiparametric imaging of biological systems by force-distance curve-based AFM"

Y.F. Dufrêne, D. Martinez-Martin, I. Medalsy, D. Alsteens, D.J. Müller

Nat. Methods (2013) 10, 847-854.

"Sequential unfolding of beta helical protein by single-molecule atomic force microscopy"

D.Alsteens, N. Martinez, M. Jamin, F. Jacob-Dubuisson

PLoS One (2013) 8, e73572.

"Unraveling the nanoscale surface properties of Chitin synthase mutants of Aspergillus fumigatus and their biological implications"

D. Alsteens, V. Aimanianda, P. Hegde, S. Pire, R. Beau, J. Bayry, J.-P. Latge, Y.F. Dufrêne

Biophysical Journal (2013) 105, 320–327.

"Single-cell force spectroscopy of Als-mediated fungal adhesion"

D. Alsteens, A. Beaussart, S. Derclaye, S. El-Kirat-Chatel, H.R. Park, P.N. Lipke, Y.F. Dufrêne

Analytical Methods (2013) 5, 3657-3662.

"Single-molecule analysis of the major glycopolymers of pathogenic and non-pathogenic yeast cells"

S. El-Kirat-Chatel, A. Beaussart, D. Alsteens, A. Sarazin, T. Jouault, Y.F. Dufrêne

Nanoscale (2013) 5, 4855-4863.

"Role of the amyloid region in the formation and propagation of Als adhesive nanodomains on Candida albicans"

D. Alsteens

Proceedings of SPIE (2013) 8590, 86900F.

"Single-cell force spectroscopy of probiotic bacteria"

A. Beaussart, S. El-Kirat-Chatel, P. Herman, D. Alsteens, J. Mahillon, P. Hols, Y.F. Dufrêne

Biophysical Journal (2013) 104, 1886-1892.

"Adhesion and nanomechanics of pili from the probiotic Lactobacillus rhamnosus GG"

Tripathi, A. Beaussart, D. Alsteens, V. Dupres, I. Claes I. Von Ossowski, W.M. De Vos, A. Palva, S. Lebeer, J. Vanderleyden, Y.F. Dufrêne

ACS Nano (2013) 7, 3685-3697.

"Nanoscale analysis of caspofungin-induced cell surface remodeling in Candida albicans"

S. El-Kirat-Chatel, A. Beaussart, D. Alsteens, D.N. Jackson, P.N. Lipke, Y.F. Dufrêne

Nanoscale (2013) 5,1105-1115.

"High-resolution imaging of chemical and biological sites on living cells using peak force tapping atomic force microscopy"

D. Alsteens, V. Dupres, S. Yunus, J.P. Latgé, J.J. Heinisch, Y.F. Dufrêne

Langmuir (2012) 28, 16738-16744.

"Single-molecule imaging and functional analysis of Als adhesins and mannans during Candida albicans morphogenesis"

A. Beaussart, D. Alsteens, S. El-Kirat-Chatel, P.N. Lipke, S. Kucharíková, P. Van Dijck, Y.F. Dufrêne

ACS Nano (2012) 12, 10950-10964.

"Chitin synthases with a myosin motor-like domain control the resistance of Aspergillus fumigatus to echinocandins"

C. Jimeńez-Ortigosa, V. Aimanianda, L. Muszkieta, I. Mouyna, D. Alsteens, S. Pire, R. Beau, S. Krappmann, A. Beauvais, Y.F. Dufrêne, C. Roncero, J.P. Latgé

Antmicrob. Agents Ch. (2012) 56, 6121-6131.

"Atomic force microscopy–looking at mechanosensors on the cell surface"

J.J Heinisch, P.N. Lipke, A. Beaussart, S. El Kirat Chatel, V. Dupres, D. Alsteens, Y.F. Dufrêne

Journal of Cell Science (2012) 125, 4189-4195.

"Unzipping a functional microbial amyloid"

D. Alsteens, C.B. Ramsook, P.N. Lipke, Y.F. Dufrêne

ACS Nano (2012) 6, 7703-7711.

"Microbial cells analysis by atomic force microscopy"

D. Alsteens

Methods in Enzymology (2012) 506, 3-17.

"Strenghtening relationships: Amyloids create adhesion nanodomains in yeasts"

P.N. Lipke, M.C. Garcia, D. Alsteens, C.B. Ramsook, S.A. Klotz, Y.F; Dufrêne

Trends in Microbiology (2012) 20, 59-65.

"A role for amyloid in cell aggregation and biofilm formation"

M.C. Garcia, J.T. Lee, C.B. Ramsook, D. Alsteens, Y.F. Dufrêne, P.N. Lipke

PLOS One (2011) 6, e17632.

"The Pseudomonas aeruginosa membranes : a target for a new amphiphilic aminoglycoside derivative?"

M. Ouberai, F. El Garch, A. Bussiere, M. Riou, D. Alsteens, L. Lins, I. Baussanne, Y. F. Dufrêne, R. Brasseur, J.L. Decout, M.P. Mingeot-Leclercq

JBiochim. Biophys. Acta-Biomembr. (2011) 6, 1716-1727.

"Frontiers in microbial nanoscopy"

D. Alsteens, V. Dupres, G. Andre, Y.F. Dufrêne

Nanomedicine (2011) 6, 395-403.

Research Papers

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